The team at Infusion Innovations and CPIE Pharmacy Services are committed to evidence based research and have invested in publishing our findings in scientific literature.

Continuous intravenous antibiotic infusions in the home site of care: Practical Tips for Providers

26(3): 24-30
The approach used to administer an antibiotic depends on the pharmacological properties of the drug and factors such as drug stability. Information provided as food for thought in a rapidly evolving health care landscape.

Safety and clinical outcomes of hospital in the home

Journal of Patient Safety
16(2): 123-129
The aim of the study was to evaluate clinical outcomes and adverse events (AEs) experienced by patients treated within the Hospital in the Home (HITH) service of a major metropolitan hospital in South Australia. A retrospective case note audit of 100 HITH episodes among adults who received continuous intravenous antimicrobial therapy via an elastomeric or electronic infusion device was undertaken. Age- and sex-adjusted binomial logistic regression analyses were undertaken to identify factors associated with major and minor AEs.

Safety of Nurse- and Self-Administered Paediatric Outpatient Parenteral Antimicrobial Therapy

9(11): 761
This study aimed to compare and contrast the safety and efficacy of nurse- and self-administered paediatric outpatient parenteral antimicrobial therapy (OPAT) models of care and to identify clinical factors associated with documented adverse events (AEs).

Flow rate accuracy of ambulatory elastomeric and electronic infusion pumps when exposed to height and back pressures experienced during home infusion therapy

Expert Review of Medical Devices
16(8): 735-42
Elastomeric infusion pumps are widely used in the delivery of parenteral medications in the home, but real-life conditions may not match calibration or standardised testing conditions. This study investigated the impact of changes in infusion pump height and/or back pressure on infusion pump function.

Evaluation of the quality of sterile compounding videos available on the YouTube video sharing website

International Journal of Pharmaceutical Compounding
23(3): 245-9
The objective of this study was to evaluate the quality of instructional sterile compounding videos posted on a popular video-sharing website (YouTube). YouTube was systematically searched using relevant terms (aseptic compounding, sterile compounding) to identify all videos demonstrating aseptic manipulations of compounded sterile preparations in a cleanroom. Promotional videos, news stories, interviews, and videos with manipulations performed outside a cleanroom, without audio or spoken in a language other than English, were excluded. Three experts independently reviewed each video and assessed the quality of key sterile compounding processes, information delivery, and overall suitability for workforce training using a standardized assessment tool.